Scivation has made pre-workout supplementation a
thoughtless endeavor. Imagine if you could take the
scientifically-proven, synergistic ingredients to guarantee you have
all bases covered and to assure that you get the skin-bursting pumps,
mind-blowing energy and unbelievable endurance to help you attack the
weights like a beast. If youï¿½re like anyone here at Team Scivation,
this is a dream come true. Time to stop dreaming.
We have formulated VasoCharge around ingredients that are
scientifically proven to increase performance and muscle growth.
VasoCharge contains synergistic ingredients that work together to take
the results you will see to the next level and beyond.
1. Creatine + Citrulline Malate
- Synergistically increases performance.
2. Creatine + Beta-Alanine
- Synergistically increases performance and lean mass gains.
3. Citrulline Malate + Arginine
- Increases blood flow and amino acid deliver to skeletal muscle, leading to increased protein synthesis (muscle growth).
4. Tyrosine + ALCAR + Caffeine
- Increases energy and mental focus while delaying fatigue, allowing you to workout harder and longer.
Lets Take A More Indepth Look At VasoCharge’s Ingredients.
(Creatine Monohydrate, Di Creatine Malate)
Creatine is used in the high-energy phosphate or
ATP-PCr system to regenerate ATP. ATP, the body’s main source of
energy, is a molecule of adenosine (adenine + the sugar ribose) linked
to three phosphate molecules by high-energy bonds. Breaking of the two
outer bonds results in the release of energy. When the most outer bond
is broken, the energy is released and ADP and Pi are left behind.
Creatine, which is bonded to a phosphate ion, transfers energy to the
ADP and Pi molecule by breaking its own bond. This regenerates the ATP
molecule, which means one now has more energy to use. Skeletal muscle
has a limited storage of creatine. Therefore supplementing with
creatine increases your ability to form ATP and therefore increases the
available energy for exercise. Creatine has been shown to:
Increase muscle size and strength (Willoughby, 2001)
Increase power output (Becque, 2000)
Increase high-intensity exercise performance (Tarnopolsky, 2000)
Increase work capacity (Rico-Sanz, 2000)
Creatine is one of the most scientifically proven-effective
supplements on the market, with creatine monohydrate being the form
used in most studies.
(Citrulline Malate, L-Arginine Alpha KetoGlutarate 2:1, (Di-L-Arginine)-L-Malate, Citric Acid, (Di-L-Arginine) Orotate)
The rate-limiting step of amino acid uptake into
skeletal muscle is the transportation of the amino acids through the
blood to the skeletal muscle, which is governed by blood flow (Wolfe,
2004). NO vasodilates blood vessels, thereby increasing blood flow.
This increase when combined with exercises means greater blood flow and
greater amino acid deliver and uptake in the working skeletal muscle.
Exercise itself results in an increase in NO production, and the
increased blood flow created by exercise is believed to be linked to
the increase in protein synthesis post workout (Douglas et al., 2004).
Di-Arginine Orotate, AAKG, Di-Arginine Malate, and Citrulline Malate
all increase NO production and blood flow to skeletal muscle.
Citrulline-Malate has been shown to increase the rate of oxidative
ATP production during exercise and the rate of phosphocreatine
replenishment post exercise (Bendahan, 2002). Increasing the rate of
ATP production during exercise would increase performance and energy.
Citrulline-Malate also has anti-fatigue properties due to its
ability to decrease ammonia levels and prevent against metabolic
acidosis (Callis, 1991). Decreasing the sensation of fatigue would
allow one to workout harder and longer, and thereby burn more calories
and lose more fat.
Both Citric Acid and Malic Acid (Malate) are intermediates in the
Krebï¿½s cycle, which produces ATP. Adding citric acid and malic acid
to VasoCharge aids in ATP production.
It has been shown that skeletal muscle carnosine levels
are correlated with performance during high-intensity exercise (Suzuki,
2002). Carnosine is an important metabolic buffer in skeletal muscle
(Suzuki, 2002), which means it helps maintain the acid-base balance in
the presence of high H+ concentrations. High levels of H+ during
exercise cause fatigue and decrease performance.
Beta-alanine is one of the two amino acids (histidine being the
other) that makes up the dipeptide carnosine
(L-beta-alanyl-L-histidine). Growing research shows Beta-alanine to be
a very effective performance enhancers and lean mass building
supplement. Research shows:
Beta-Alanine availability is the limiting factor in muscle carnosine synthesis (Hill, 2007).
Muscle carnosine levels were higher after 10 weeks of
beta-alanine supplementation than after 4 weeks, showing that
beta-alanineï¿½s effects are best experienced over long term
supplementation (Hill, 2007).
Beta-alanine supplementation increases total work done during aerobic exercise (Hill, 2007).
Beta-alanine enhances endurance performance (Zoeller, 2006)
Beta-Alanine delays the onset of neuromuscular fatigue (Stout, 2006)
Adding beta-alanine to creatine supplementation leads to greater increases in lean mass than creatine alone (Hoffman, 2006).
It is clear that current research shows Beta-Alanine to be an
effective performance enhancer and enhances lean mass gains when
combined with creatine.
N-acetyl-cysteine (NAC) is derived
from the non-essential amino acid cysteine. Because cysteine is very
unstable, supplementing with NAC allows one to get the benefits of
cysteine. NAC is an antioxidant itself (Aruoma, 1989) and is also used
to synthesize the antioxidant glutathoine. Glutathione is a powerful
antioxidant and also regenerates vitamin C and E (Bounous, 1999)
Since intense exercise depletes glutathione (Sen, 1999),
supplementation of NAC can is beneficial to increase glutathione
levels. Oxidative stress caused by free radicals (H+), causes fatigue
and muscular soreness. Supplementing with NAC will enhance athletic
performance by scavenging these free radicals (Lands, 1999).
(N-Acetyl Tyrosine, ALCAR, Caffeine)
Tyrosine is a nonessential amino acid
used to make the catecholamine neurotransmitters dopamine,
norepinephrine, and epinephrine, thyroid hormones, and the skin pigment
melanin. Stress, such as exercise, depletes the amount of dopamine and
norepinephrine in the brain. Tyrosine supplementation has been shown to:
Decrease the negative effects of stress (Banderet, 1989)
Decrease fatigue and increase cognitive performance (Neri, 1995)
Decrease cardiovascular stress and enhance cognitive activity (Dollins, 1995)
The amino acid L-Carnitine plays a vital role
in energy metabolism, specifically the transport of fatty acids into
mitochondria where they can be oxidized. ALCAR is the acetylated form
of carnitine and is the most popular form of supplemental carnitine.
ALCAR is a potent antioxidant shown to have cognitive enhancing and
adaptogen properties. ALCAR increases exercise performance by
Increasing fat oxidation (Hongu, 2003)
Decreasing muscle soreness (Giamberardino, 1996)
Decreasing lactic acid accumulation (Siliprandi, 1990).
Caffeine, a plant alkaloid
belonging to the drug class methylxanthines and is found in natural
sources such as coffee beans, tea leaves, cocoa beans, and other
plants, is the worldï¿½s most widely used stimulant. Caffeine is a
Central Nervous System (CNS) stimulant shown to delay fatigue and
improve cognitive performance.
Caffeine acts as an adenosine receptor antagonist. Adenosine
decreases the release of stimulatory/excitatory neurotransmitters (i.e.
norepinephrine [NE]). Therefore, blocking the adenosine receptor allows
a greater excitation to occur by increasing NEï¿½s ability to activate
the adrenergic receptors.
Caffeine inhibits phosphodiesterase (PDE), causing a build-up of
cAMP levels and greater effect of NE on fatty acid lipolysis. PDE
blunts lipolysis; therefore inhibiting PDE allows lipolysis to proceed
at an accelerated rate. The end result is there are more fatty acids
available for oxidation after consumption of caffeine, which is one of
the ways caffeine is believes to increase performance.
D,L-Phenylalanine is a 50/50 mix
of D-Phenylalanine and L-Phenylalanine. L-Phenylalanine is an essential
amino acid while D-Phenylalanine is a non-protein amino acid that is
not used in protein synthesis. Phenylalanine can be metabolized to PEA
and is also a precursor for norepinephrine and dopamine.